Hi! Sikora, M. et al. Jobs People Learning Dismiss Dismiss. Disease-modifying, readily available, and easily affordable medical therapies for hypertension are ubiquitous and set a high bar for any new therapeutic. Second, the ancestry of individuals associated with the Epigravettian culture (Villabruna cluster), which was found to genetically connect European and Near Eastern hunter-gatherers, reached southern Europe well before the transition between the Early and Late Epigravettian4,15 and possibly as early as the GravettianEpigravettian transition. Sci. Data warehousing is a field that has to be done right. Notably, and contrary to the report by Fu et al.4, another Gravettian-associated population from centralwestern Europe (Goyet in Belgium, n=6 individuals) is both geographically and genetically intermediate between the Vstonice and Fournol clusters. Curr. With a lot of raw data, you need to put in some work. From around 8ka, we begin to observe admixture events with Sidelkino ancestry in central Europe. Proc. "Presumably, these people came from the Balkans, arrived first in northern Italy around the time of the glacial maximum and spread all the way south to Sicily.". Vallini, L. et al. Trans. Known to have been the coldest phase of the last Ice Age, the LGM is considered to have caused a demographic decline in large parts of Europe10, with populations retracting to southern latitudes as attestedfor exampleby the contemporaneity of the Solutrean culture (2419ka) in the Iberian peninsula and southern France. 2b). We also genotyped a selection of previously published individuals with the same approach (Supplementary Data 1.G)2,4,30,74,75,76,77,78. CAS Echinacea. We report 47 new radiocarbon dates performed on skeletal elements of 40 individuals by the Curt-Engelhorn-Zentrum Archaeometrie in Mannheim (MAMS, n=29), Center for Isotope Research, University of Groningen (GrA and GrM, n=5), University of Aarhus (AAR, n=3), Beta Analytics (Beta, n=2), Zrich (ETH, n=3), International Chemical Analysis (ICA, n=2), Natural History Museum in Paris (Echo Lab, n=1) and Vilnius (FTMC, n=2) (Supplementary Data 1.A). These authors contributed equally: Cosimo Posth, He Yu, Archaeo- and Palaeogenetics, Institute for Archaeological Sciences, Department of Geosciences, University of Tbingen, Tbingen, Germany, Senckenberg Centre for Human Evolution and Palaeoenvironment at the University of Tbingen, Tbingen, Germany, Cosimo Posth,Dorothe G. Drucker,Herv Bocherens,Christoph Wiing,Nicholas J. Conard&Katerina Harvati, Department of Archaeogenetics, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany, Cosimo Posth,He Yu,Ayshin Ghalichi,Hlne Rougier,Yilei Huang,Harald Ringbauer,Adam B. Rohrlach,Kathrin Ngele,Vanessa Villalba-Mouco,Rita Radzeviciute,Tiago Ferraz,Alexander Stoessel,Rezeda Tukhbatova,Wolfgang Haak&Johannes Krause, State Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking University, Beijing, China, Department of Anthropology, California State University Northridge, Northridge, CA, USA, Universit de Bordeaux, CNRS, MC, PACEA UMR 5199, Pessac, France, Isabelle Crevecoeur,Andr Morala,Stphane Madelaine,Priscilla Bayle,Bruno Maureille,Jean-Guillaume Bordes&Mona Le Luyer, School of Mathematical Sciences, University of Adelaide, Adelaide, South Australia, Australia, Instituto Universitario de Investigacin en Ciencias Ambientales de Aragn, IUCA-Aragosaurus, Zaragoza, Spain, Department of Archaeogenetics, Max Planck Institute for the Science of Human History, Jena, Germany, Institute of Zoology and Evolutionary Research, University of Jena, Jena, Germany, Center of Excellence Archaeometry, Kazan Federal University, Kazan, Russia, Department of Biology, University of Florence, Florence, Italy, Martina Lari,Alessandra Modi&Stefania Vai, Estonian Biocentre, Institute of Genomics, University of Tartu, Tartu, Estonia, Tina Saupe,Christiana L. Scheib&Luca Pagani, St Johns College, University of Cambridge, Cambridge, UK, Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Palermo, Italy, Department of Biology, University of Padova, Padova, Italy, Department of Chemistry G. Ciamician, Alma Mater Studiorum, University of Bologna, Bologna, Italy, Department of Human Evolution, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany, UMR 8068 CNRS, TEMPSTechnologie et Ethnologie des Mondes Prhistoriques, Nanterre Cedex, France, Laurent Klaric,Olivier Bignon-Lau,Grgory Debout,Michel Orliac,Pierre Bodu,Bndicte Souffi&Frdrique Valentin, Muse National de Prhistoire, Les Eyzies de Tayac, France, UMR 5140 CNRS, Archologie des Socits Mditerranennes, Universit Paul-Valry, Montpellier, France, UMR 7194, Histoire Naturelle de lHomme Prhistorique (HNHP), Dpartement Homme et Environnement, Musum National dHistoire Naturelle, CNRS, UPVD, Paris, France, Association APRAGE (Approches pluridisciplinaires de recherche archologique du Grand-Est), Besanon, France, Skeletal Biology Research Centre, School of Anthropology and Conservation, University of Kent, Canterbury, UK, Dipartimento di Scienze Fisiche, della Terra e dellAmbiente, U.R. Tina Huang is a prominent data scientist, previously working at a FAANG company, and has been an active YouTuber, creating data science content for nearly a decade. A series of f4-symmetry statistics confirm that all the Epigravettian-associated individuals are cladal, and do not share excess affinity with any local (Paglicci 12) or non-local preceding ancestries (Goyet Q116-1, Kostenki 14, Malta 1 or Vstonice) (Supplementary Data 2.F). Cosimo Posth, He Yu, Ayshin Ghalichi, Hlne Rougier, Isabelle Crevecoeur, Yilei Huang, Harald Ringbauer, Adam B. Rohrlach, Kathrin Ngele, Vanessa Villalba-Mouco, Rita Radzeviciute, Tiago Ferraz, Alexander Stoessel, Rezeda Tukhbatova, Dorothe G. Drucker, Martina Lari, Alessandra Modi, Stefania Vai, Tina Saupe, Christiana L. Scheib, Giulio Catalano, Luca Pagani, Sahra Talamo, Helen Fewlass, Laurent Klaric, Andr Morala, Mathieu Ru, Stphane Madelaine, Laurent Crpin, Jean-Baptiste Caverne, Emmy Bocaege, Stefano Ricci, Francesco Boschin, Priscilla Bayle, Bruno Maureille, Foni Le Brun-Ricalens, Jean-Guillaume Bordes, Gregorio Oxilia, Eugenio Bortolini, Olivier Bignon-Lau, Grgory Debout, Michel Orliac, Antoine Zazzo, Vitale Sparacello, Elisabetta Starnini, Luca Sineo, Johannes van der Plicht, Laure Pecqueur, Gildas Merceron, Graldine Garcia, Jean-Michel Leuvrey, Coralie Bay Garcia, Asier Gmez-Olivencia, Marta Potowicz-Bobak, Dariusz Bobak, Mona Le Luyer, Paul Storm, Claudia Hoffmann, Jacek Kabaciski, Tatiana Filimonova, Svetlana Shnaider, Natalia Berezina, Borja Gonzlez-Rabanal, Manuel R. Gonzlez Morales, Ana B. Marn-Arroyo, Beln Lpez, Carmen Alonso-Llamazares, Annamaria Ronchitelli, Caroline Polet, Ivan Jadin, Nicolas Cauwe, Joaquim Soler, Neus Coromina, Isaac Ruf, Richard Cottiaux, Geoffrey Clark, Lawrence G. Straus, Marie-Anne Julien, Silvia Renhart, Dorothea Talaa, Stefano Benazzi, Matteo Romandini, Luc Amkreutz, Herv Bocherens, Christoph Wiing, Sbastien Villotte, Javier Fernndez-Lpez de Pablo, Magdalena Gmez-Puche, Marco Aurelio Esquembre-Bebia, Pierre Bodu, Liesbeth Smits, Bndicte Souffi, Rimantas Jankauskas, Justina Kozakait, Christophe Cupillard, Hartmut Benthien, Kurt Wehrberger, Ralf W. Schmitz, Susanne C. Feine, Tim Schler, Corinne Thevenet, Dan Grigorescu, Friedrich Lth, Andreas Kotula, Henny Piezonka, Franz Schopper, Ji Svoboda, Sandra Szelov, Andrey Chizhevsky, Aleksandr Khokhlov, Nicholas J. Conard, Frdrique Valentin, Katerina Harvati, Patrick Semal, Bettina Jungklaus, Alexander Suvorov, Rick Schulting, Vyacheslav Moiseyev, Kristiina Mannermaa, Alexandra Buzhilova, Thomas Terberger, David Caramelli, Eveline Altena, Wolfgang Haak, Johannes Krause. People with a new gene pool settled in these areas, instead. Lifetime access to all course materials and updates. Key, F. M. et al. ), no. c, MDS plot of European hunter-gatherers based on 1f3(Mbuti; pop1, pop2). 7,794 followers. Fu, Q. et al. Extended Data Fig. I am super excited to join the 365 Data Use Cases series, and in this post, I will share insights about my favorite data use case: product development. They were different in many aspects, including their skin and eye colour," says He Yu. 4, 11 (2007). Dashed lines show the frequencies estimated for the indicatedpresent-day 1000 GenomesProject populations (CEU, Utah residents of northern and westernEuropean ancestry; GBR, British; IBS, Spanish;TSI,Tuscan)37. Modern humans began to spread across Eurasia around 45,000 years ago but previous research showed that the first modern humans that arrived in Europe did not contribute to later populations. Lipson, M. et al. The aligned sequences of all individuals with new genomic data reported in this study are available at the European Nucleotide Archive (ENA) under study accession number PRJEB51862. I Agree, Brandwatch Bulletin #41: 7 Women in Tech You ShouldKnow. Rep. 10, 21931 (2020). Author pages are created from data sourced from our academic publisher partnerships and public sources. ScienceDaily, 1 March 2023. You can also check out our video on the topic below or scroll down to keep on reading. Google Scholar. Negative and positive controls were carried alongside each experiment. The expansion of farming by9,8, 7.5 and7 kais shown as green shades. The previous inhabitants may have migrated to the north as their habitat, the 'mammoth' steppe, dwindled," says Johannes Krause, the study's senior author. Commun. YOUTH VAPING: AN ANALYSIS OF AN EPIDEMIC 6 Youth Vaping: An Analysis of an Epidemic 'Vape.' In the 1980s, this was a phrase used to describe weapon uselimited primarily to science fiction writing. Anyone you share the following link with will be able to read this content: Sorry, a shareable link is not currently available for this article. Hi friends! Nat. View Tina Huang's profile on LinkedIn, the world's largest professional community. She has been working for the data sciences industry since 2014. Moreover, previous studies have shown that El Mirn carries a genetic contribution from the Villabruna cluster, which is found in Epigravettian-associated individuals from Italy4,15. During this time agriculture and a sedentary lifestyle spread from Anatolia to Europe. Biol. This button displays the currently selected search type. performed or supervised laboratory work. Radiocarbon 62, 725757 (2020). Kircher, M., Sawyer, S. & Meyer, M. Double indexing overcomes inaccuracies in multiplex sequencing on the Illumina platform. As previously hinted37, we find a large frequency variation in alleles related to skin and eye pigmentation among post-LGM hunter-gatherer groups. My name is Tina Huang and I'm a data scientist at a FAANG company. The length of each coloured bar represents the fraction of individuals carrying the corresponding haplogroup (legend on the right of each panel). Lead Advisor - Data Science. Oxidation of methane into valuable chemicals, such as C 2+ molecules, has been long sought after but the dilemma between high yield and high selectivity of desired products remains. Mol. Damgaard, P. et al. Test cases development, automated test tool design, and validation testing for Alaris' first attachable/detachable infusion pump, which is . Previously worked at Goldman Sachs and the Ontario Institute for . Billed once. Tina Huang Data Scientist. Nat. Unlike setting up a Premium subscription to our platform, for which you would be billed monthly or annually, acquiring individual courses requires a one-time payment only. Quat. A software engineer who now works as a content creator full-time, Mayuko Inoue runs a YouTube channel dedicated to software engineering, working in the tech industry, and life in general. 5). The analysis of biological relatedness was performed by calculating relatedness coefficient (r) based on PMR on the autosomal SNPs (Supplementary Data 1.F and Supplementary Information, section4). 9) and testing the relative affinity among them using f4-statistics in the form f4(Mbuti, Epigravettian A; Epigravettian B, Epigravettian C) (Supplementary Data 2.E). Sikora, M. et al. Individuals in western and southwestern Europe related to the Fournol cluster are consistently deposited in cave sites and occasionally exhibit anthropogenic marks whereas individuals related to the Vstonice cluster are buried with grave goods and/or personal ornaments and ochre in open air or cave sites in central-eastern and southern Europe, respectively (Supplementary Figs. In this episode we go through a couple really superb resumes that you should model yours after. 2014-2020.4.01.16-0030) and C.L.S. Antiquity 91, 573588 (2017). Ancient genomes from present-day France unveil 7,000 years of its demographic history. Genome-wide patterns of selection in 230 ancient Eurasians. 9 Graphical summary depicting the main genetic transformations in post-40 ka hunter-gatherers from Europe. This is further validated by f4-statistics of the form f4(Mbuti, Arene Candide 16; Goyet Q-2, Magdalenian-associated individuals), which is significantly positive only for El Mirn, whereas all other tested individuals and Goyet Q-2 are symmetrically related with respect to Arene Candide 16 (Supplementary Fig. Instagram has an infinite scroll, and Uber has different options such as UberXL and Uber Pool. The MDS analysis showing the genetic affinity among European hunter-gatherers was based on the distance matrix derived from outgroup f3-statistics, in the form 1f3(Mbuti.DG; pop1, pop2) and performed with classical MDS algorithm (cmdscale) implemented in R 3.5.1. Article b, Population diversity shown by PMR between individuals in different groups. Thats it for today. This channel is about data science, learning, and productivity. First up is the MIT researcher and YouTuber Jordan Harrod. 2c). Don't be shy, get in touch. Hajdinjak, M. et al. Feldman, M. et al. Nature 514, 445449 (2014). Its mainly used in industries such as finance, insurance, healthcare, and insurance-related apps such as credit card applications, vehicle purchasing, etc. USA 111, 22292234 (2014). Follow. 6). How to Become a Data Scientist at FAANG (Ft. Tina Huang) In this video, I had the opportunity to talk with Tina Huang, a Data Scientist at one of the FAANG companies. & Hlie, J. F. Temperature and precipitation regime in LGM human refugia of southwestern Europe inferred from 13C and 18O of large mammal remains. 359, 318 (2015). Fu, Q. et al. The key areas to focus on when getting started in data science [6:01] Tina's five steps to consistently doing anything [11:55] Tina's day-to-day life as a data scientist at one of the world's largest tech companies [20:02] How Tina's computer science background helps her work [26:20] Traditional banking culture vs big tech [32:12] Taipei, Taiwan . Instead, in southern Europe, a distinct hunter-gatherer genetic profile was found as early as 17ka in individuals associated with the Epigravettian culture15 (2412ka, from the Italian peninsula to the southeastern European Plain across the Balkans). You need more data until you have the right ingredients to make a good recipe, but you also need less data until you have the right amount of ingredients to make a bad recipe. c, Admixture graph modelling of the main pre-LGM European hunter-gatherer lineages created using qpGraph. Evol. H. Rougier received support from the College of Social and Behavioral Sciences of CSUN and the CSUN Competition for RSCA Awards. Tina is excellent when it comes to getting overall data science career advice. The compiled genotype file used for analyses, including re-genotyped published genomes, has been uploaded at the Edmond Data Repository of the Max Planck Society (https://edmond.mpdl.mpg.de/dataset.xhtml?persistentId=doi:10.17617/3.Y1KJMF). Consultant - October 2015 to June 2016. Notes 9, 88 (2016). Nowadays, we take it for granted that these features exist, but the integrity of those products is, in fact, a labor of love. The cleaned reads with base quality and mapping quality over 30 were piled up with mpileup in SAMtools 1.373 on the 1240k targeted sites. 4a). My name is Tina and I'm a data scientist and YouTuber. Adv. In other cases, you may have to create a more complex database structure (such as SQLite). Emergence of human-adapted Salmonella enterica is linked to the Neolithization process. A draft sequence of the Neandertal genome. Google Scholar. Here we analyse 356 ancient hunter-gatherer genomes, including new genomic data for 116 individuals from 14 countries in western and central Eurasia, spanning between 35,000 and 5,000 years ago. Huang, Y. This free online conference is featuring panel discussions from Nat. Overall, the literature suggests that Chinese Canadian students demonstrate high levels of achievement and that this academic success is associated with factors such as stronger feelings of ethnic identity, better English language skills in the family, Chinese . In this video @Tina Huang and I go through 5 subscriber submitted resumes and review them. Dismiss. 1 and 2). The human remains were processed in dedicated laboratories at the Max Planck Institute for the Science of Human History in Jena (Germany), University of Tbingen (Germany), University of Florence (Italy), Leiden University Medical Center (the Netherlands) and University of Tartu (Estonia). Freshwater radiocarbon reservoir effects at the burial ground of Minino, Northwest Russia. Gonzlez-Fortes, G. et al. Ecol. has received funding from the Van de Kamp fonds. Develped strategies for promoting G-Mark to Taiwan. As long asyouget a exam score of 60% or above,youare eligible toreceive aCourse Certificate! 9). de Lige, 2021). View Tina Zhang's business profile as Brand Specialist at Dymind Biotechnology. Hunter-gatherers across the great Adriatic-Po region during the Last Glacial Maximum: environmental and cultural dynamics. YSYS stands for Your Startup, Your Story and is dedicated to connecting diverse people with opportunities in tech.. Further palaeogenomic studies on Upper Palaeolithic individuals from the Balkans will be essential for understanding whether southeastern Europe represents the source of the Villabruna ancestry and a climatic refugium for human populations during the LGM. The ancestry found in individuals associated with the preceding Aurignacian culture from central Europe (GoyetQ116-1ancestry) gave rise to Gravettian-associated individuals from western and southwestern Europe. Her channel is about data science, transitioning into computer science and software engineering. Within Sicily, the 14ka Oriente C individual shows higher affinity with the much younger but geographically closer 10ka Uzzo group30 (n=2) than with the almost contemporaneous San Teodoro 2 individual from eastern Sicily. What is Kagi Chart in Data Visualization? Quat. and H.F. produced a subset of the radiocarbon dates. Tina Huang I'm a data scientist, youtuber, and the first Lonely Octopus . Do you agree to our cookie policy? Sci. My experience includes an internship at Goldman Sachs where I did some machine learning work before I took up my current data science job in tech. Considering a freshwater reservoir signal in the upper Volga region making radiocarbon dates on human remains appear up to about 500 years older than their true age44, there could be an interval of more than 1,000 years between the first evidence of admixture in central European hunter-gatherers with Sidelkino ancestry and eastern European hunter-gatherers with Oberkassel ancestry. Saag, L. et al. 1). Int. We explain it all step-by-step, including how to download and install the necessary software, e.g., Excel, Anaconda, Jupyter Notebook, Python, R, MySQL, Tableau Public, etc. A genome sequence from a modern human skull over 45,000 years old from Zlat k in Czechia. Moreover, the almost complete genetic replacement of the Magdalenian-associated gene pool raises the hypothesis that parts of Europe were differentially populated during the abrupt climatic variation starting around 14.7ka with the BllingAllerd warming period, creating areas where southern European populations could expand. Max Planck Institute for Evolutionary Anthropology. Fog computing is a computing structure which is distributed in nature. The dimensions are calculated using newly reported and previously published hunter-gatherer groups or individuals with more than 30,000 SNPs.
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